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KMID : 1011720180110020082
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International Journal of Thyroidology
2018 Volume.11 No. 2 p.82 ~ p.87
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Skin-Related Toxicity of Tyrosine Kinase Inhibitor in Thyroid Cancer
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Lim Dong-Jun
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Abstract
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Skin-related toxicity is one of the most important adverse events from multi-target tyrosine kinase inhibitor (MTKI) to treat radioiodine refractory thyroid cancer. As hand foot skin reaction can limit quality of life and therapeutic effectiveness, it is essential to cope with a variety of severity of skin-related toxicity induced by MTKI. Herein, we will discuss two representative cases of skin-related toxicities which were managed by discontinuation/reduction of therapeutic doses of MTKI and were treated by proper medication in thyroid cancer patients with distant metastasis.
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KEYWORD
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Thyroid neoplasms, Protein kinase inhibitors, Hand-foot syndrome
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